PDRN, or Polydeoxyribonucleotide, is made up of purified DNA fragments that have been studied for their potential role in skin repair and regeneration. In aesthetic dermatology, PDRN treatment is explored for supporting skin hydration, texture, elasticity, and overall skin rejuvenation. It is sometimes called “Salmon DNA” because some PDRN and related DNA-derived products are sourced from salmon or trout.